124912
Identification, Pathophysiology, and Clinical Implications of Primary Insulin Hypersecretion
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Primary insulin hypersecretion (independent of insulin resistance) is linked to a worse metabolic profile and predicts the future development of type 2 diabetes. higher liver insulin resistance
Published in on December 20, 2018, this study focuses on individuals who secrete excessive insulin despite having normal glucose tolerance. 124912
Researchers analyzed 1,168 nondiabetic adults and 182 obese adolescents using glucose tolerance tests and hyperglycemic clamps.
Hypersecretors showed a 53% increase in insulin secretion, higher liver insulin resistance, and increased fat mass compared to normosecretors. Other Articles Using "124912"