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: Retinoic acid (RA) signals through nuclear receptors ( RAR , , and

) and heterodimers. These complexes bind to Retinoic Acid Response Elements (RAREs) in DNA to regulate the expression of hundreds of genes. 21702.rar

is a driver in certain cancers, such as T-cell lymphoma, where synthetic retinoids are tested as targeted therapies. : Retinoic acid (RA) signals through nuclear receptors

: Rosemary extracts are explored as natural alternatives to synthetic retinoids for anti-aging and UV protection. Oncology : RAR such as T-cell lymphoma

: RAR signaling is critical for adult neurogenesis and stem cell differentiation. Summary of RAR Isotypes