Found to be upregulated in the HCC microenvironment, agrin promotes cancer cell proliferation and "stiffness" of the tumor tissue, which helps the cancer spread.
Proteoglycans (PGs) are heavily glycosylated proteins found in the extracellular matrix (ECM). In the context of liver cancer, they act as a "double-edged sword," either promoting or inhibiting tumor progression depending on their specific type and the stage of the disease. Key Proteoglycans and Their Roles 27879.rar
Proteoglycans in Cancer: The Case of Hepatocellular Carcinoma (HCC) Found to be upregulated in the HCC microenvironment,