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Because DHEA is a hormone, quality control is critical. Over-the-counter (OTC) products often vary significantly in potency, sometimes containing 0% to 150% of the labeled amount. DHEA - Mayo Clinic
DHEA is most effective when treating documented hormone deficiencies or specific medical issues rather than as a general wellness supplement: buy dhea supplement
: It is "likely effective" for treating thinning vaginal tissue (vaginal atrophy) in postmenopausal women. FDA-approved vaginal inserts are available for this purpose. Because DHEA is a hormone, quality control is critical
: It may improve mood and libido in women with primary or secondary adrenal insufficiency who still feel unwell despite standard hormone replacement. Quality and Purchasing Considerations FDA-approved vaginal inserts are available for this purpose
: In women with diminished ovarian reserve, some studies suggest DHEA may improve egg quality, increase pregnancy rates, and lower miscarriage risks when taken under medical supervision for 6–12 weeks before IVF.
: Some evidence indicates it may be "possibly effective" for improving mood in people with low DHEA levels, though it is not a first-line therapy.