Mercedes S-class W221 1.45 -

: The cabin replaced many plastic surfaces with higher-end leather, wood, and metal. High-end options include massaging seats with four modes and active ventilation. Engine Options & Reliability

: Uses infrared technology to see pedestrians at night.

The , produced from 2006 to 2013 , is widely considered one of the finest luxury flagships of its era, marking a significant return to form for Mercedes after the reliability criticisms of the previous W220 model. While it offers exceptional comfort and pioneering technology, it requires a "luxury maintenance" budget to remain reliable on the used market. Key Highlights MERCEDES S-CLASS W221 1.45

: Predicts collisions and can automatically apply maximum braking pressure.

: An advanced adaptive cruise control that can bring the car to a full stop in traffic. : The cabin replaced many plastic surfaces with

: This generation introduced several high-tech features still impressive today:

Reliability varies significantly by the engine and production year. The (Phase 2) is generally recommended as it resolved several early mechanical issues. The , produced from 2006 to 2013 ,

: The W221 provides a quiet, composed ride with excellent sound deadening and thick glass. All models, despite their size, are noted for handling like smaller cars.