Interventional neuroradiology demands a 3D understanding of vascular anatomy, focusing on flow dynamics, collateral pathways, and dangerous anastomoses to navigate procedures safely. Key areas include the seven segments of the Internal Carotid Artery, the Circle of Willis, the stroke-prone MCA, the posterior circulation, and critical ECA-ICA connections. Understanding these, alongside venous anatomy for interventions like sinus stenting, is vital for accessing and treating intracranial pathology.