Ninahd -

For further technical details, the full study is available through the ACS Sensors journal .

: Unlike traditional analytical methods like mass spectrometry, NINAHD does not require the translocation or unfolding of large molecules, allowing it to identify modifications even on proteins too large to pass through the pore. NinaHD

: The method uses hydroxylamine to treat N-acetylation, which produces acetohydroxamic acid (AHA) . This AHA molecule then serves as a "reporter" that is specifically sensed by a modified protein nanopore (PBA-modified MspA). For further technical details, the full study is