Many security communities, including Bleeping Computer , recommend a full disk wipe, reformatting, and reinstalling the OS as the only way to ensure the machine is completely clean. If Attempting Removal Without Reinstalling
Microsoft Defender Antivirus and the Microsoft Safety Scanner are designed to detect and remove this threat family. Removal Of W32-Ramnit Is Now Possible – AZMATH
Because the malware can block active security software, it is best to run these scans in Safe Mode with Networking or use a bootable rescue disk. Many security communities