: Tensions remain high between Nurse April Sexton and Dr. Ethan Choi after their breakup. Their relationship is further complicated when Ethan's sister, Emily, is brought into the ED and discovered to be pregnant, sparking a moral debate between Ethan and the pro-life April. A Major Departure: Dr. Sarah Reese
: Following Reese's resignation, Dr. Charles is seen lashing out at a new medical student as he struggles with the guilt and loss of his "daughter-like" mentee. Power Struggles and the Hybrid Suite [S4E1] Be My Better Half
: Dr. Connor Rhodes is prepared to leave for a job at the Mayo Clinic, but a surprise donation allows for the creation of a "hybrid suite" in the ED—a project he had championed. It is later revealed that Dr. Ava Bekker secured this funding by making a questionable deal with Connor’s father, Cornelius Rhodes. New Faces at Gaffney : Tensions remain high between Nurse April Sexton and Dr
: Following Dr. Will Halstead’s proposal in the season 3 finale, it is confirmed that Dr. Natalie Manning said yes. However, their "engagement bliss" is short-lived; Will pushes for a grand wedding while Natalie prefers something small, leading to early friction in their future plans. A Major Departure: Dr