then phosphorylates Threonine 256 within the kinase domain.
: SGK1 often acts as an oncogene , promoting tumor cell proliferation, metastasis, and resistance to therapies (e.g., Akt inhibitors) in breast, colon, and prostate cancers. SGK1 4 zip
SGK1 acts as a "hub" molecule regulating diverse cellular processes: then phosphorylates Threonine 256 within the kinase domain
: SGK1 stimulates intestinal glucose absorption via SGLT1 and promotes cellular glucose uptake in various tissues. promoting tumor cell proliferation