It allows researchers to visualize brain structures spanning from superficial layers down to 900 μm depth in a single study.
Experiments have shown its capability to study both morphology (structural) and neuronal activity (functional) in mouse brains. 4. Implementation and Data Handling
It achieves cellular resolution across an ultra-large FOV exceeding 50 mm². VAM_GS.Qiao.2.var
Effective imaging up to 900 μm in the mouse brain, crucial for studying deep cortical layers.
Custom-written software, frequently using LabVIEW 2020 (National Instruments). It allows researchers to visualize brain structures spanning
Capable of visualizing neuronal activity across a spatial range of over 7 mm. 2. Components of the Adaptive System
Optimized for in vivo studies, involving anaesthetized animals to maintain consistency. Capable of visualizing neuronal activity across a spatial
The system produces large, dense 3D datasets requiring advanced denoising, sometimes utilizing "zero-shot learning" methods to process weak fluorescence signals without pre-training on existing data. Summary of Performance (2026) Capability Field of View Imaging Depth Spatial Range Volume Coverage Resolution Cellular resolution