122348 Today

Identifying such a large number of specific DMRs offers potential for developing highly accurate molecular diagnostics to classify polyp risk, potentially distinguishing between aggressive polyps and benign ones. 3. Comparison and Methodology

Each adenoma subtype was directly compared to normal tissue to identify unique methylation signatures. 122348

The researchers used these 122,348 regions to create unique methylation "signatures" for different types of adenomas—specifically Sessile Serrated Lesions (SSL), Traditional Serrated Adenoma (TSA), and VA/TVA (Villous/Tubulovillous Adenoma). Identifying such a large number of specific DMRs